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Kotha Subbaramaiah Selected Research

Cyclooxygenase 2 (Cyclooxygenase-2)

5/2011Macrophages induce COX-2 expression in breast cancer cells: role of IL-1β autoamplification.
5/2010Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents.
4/2009Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway.
12/2008Cyclooxygenase-2-derived prostaglandin E2 stimulates Id-1 transcription.
9/2008NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer.
8/2008Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid.
7/2006NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells.
11/2005HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.
8/2005Levels of prostaglandin E metabolite, the major urinary metabolite of prostaglandin E2, are increased in smokers.
6/2005Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer.
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Kotha Subbaramaiah Research Topics

Disease

38Neoplasms (Cancer)
01/2017 - 01/2002
23Carcinogenesis
06/2014 - 08/2002
20Breast Neoplasms (Breast Cancer)
01/2020 - 05/2002
19Inflammation (Inflammations)
01/2022 - 07/2006
12Obesity
01/2022 - 03/2011
6Oral Leukoplakia
04/2012 - 08/2002
5Squamous Cell Carcinoma of Head and Neck
11/2009 - 08/2002
4Li-Fraumeni Syndrome
01/2020 - 03/2014
4Colonic Neoplasms (Colon Cancer)
04/2015 - 07/2007
3Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2020 - 03/2004
3Pain (Aches)
01/2019 - 10/2003
3Colitis
11/2015 - 12/2007
2Hypertrophy
04/2017 - 04/2013
2Weight Loss (Weight Reduction)
08/2015 - 11/2013
2Adenoma (Adenomas)
12/2012 - 08/2008
2Overweight
04/2012 - 07/2011
2Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2012 - 04/2007
2Lung Neoplasms (Lung Cancer)
03/2010 - 09/2008
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2008 - 06/2005
1Hypoxia (Hypoxemia)
01/2019
1Insulin Resistance
01/2017
1Weight Gain
08/2015
1Squamous Intraepithelial Lesions
01/2012
1Coinfection
01/2012
1Infections
01/2012
1Acquired Immunodeficiency Syndrome (AIDS)
01/2012
1Skin Neoplasms (Skin Cancer)
09/2010
1Disease Progression
11/2009
1Pneumonia (Pneumonitis)
04/2009
1Cardiovascular Diseases (Cardiovascular Disease)
04/2009

Drug/Important Bio-Agent (IBA)

23Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2011 - 05/2002
18Aromatase (CYP19)IBA
01/2022 - 05/2006
15Hormones (Hormone)IBA
01/2019 - 05/2004
13ProstaglandinsIBA
01/2019 - 08/2002
11Dinoprostone (PGE2)FDA Link
01/2019 - 10/2002
11Estrogens (Estrogen)FDA Link
04/2017 - 05/2004
10Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
11/2009 - 08/2002
9EnzymesIBA
04/2017 - 08/2002
9Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
10/2013 - 01/2002
9Prostaglandins EIBA
04/2012 - 08/2003
8Proteins (Proteins, Gene)FDA Link
06/2014 - 05/2002
8SmokeIBA
03/2010 - 01/2005
6Prostaglandin-E SynthasesIBA
01/2020 - 08/2003
6Celecoxib (Celebrex)FDA Link
08/2008 - 10/2002
5Biomarkers (Surrogate Marker)IBA
11/2013 - 03/2011
4Transcription Factors (Transcription Factor)IBA
01/2020 - 07/2006
4Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
06/2014 - 07/2008
4Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA
06/2014 - 11/2008
47- hydroxy- 5,11- dioxotetranorprostane- 1,16- dioic acidIBA
01/2012 - 08/2005
4Messenger RNA (mRNA)IBA
01/2012 - 08/2003
415-hydroxyprostaglandin dehydrogenaseIBA
09/2010 - 02/2006
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2015 - 02/2006
3Cytochrome P-450 CYP1A1 (CYP1A1)IBA
06/2014 - 11/2008
3Fatty Acids (Saturated Fatty Acids)IBA
11/2013 - 03/2011
3human ERBB2 proteinIBA
10/2013 - 10/2002
3ErbB Receptors (EGF Receptor)IBA
10/2007 - 01/2005
2LeptinIBA
04/2017 - 01/2017
2C-Reactive ProteinIBA
04/2017 - 01/2017
2Heat-Shock Proteins (Heat-Shock Protein)IBA
06/2014 - 11/2008
2Benzo(a)pyreneIBA
06/2014 - 04/2012
2LigandsIBA
06/2014 - 04/2012
2Pharmaceutical PreparationsIBA
11/2013 - 10/2013
2Toll-Like Receptor 4IBA
11/2013 - 12/2007
2Progesterone Receptors (Progesterone Receptor)IBA
04/2013 - 04/2012
2AzoxymethaneIBA
12/2012 - 12/2007
2Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/2009 - 05/2004
2Protein Isoforms (Isoforms)IBA
08/2008 - 04/2004
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
09/2007 - 01/2005
1Sirtuin 1IBA
01/2019
1Pioglitazone (Actos)FDA Link
01/2018
1AdiponectinIBA
01/2018
1Insulin (Novolin)FDA Link
04/2017
1Triglycerides (Triacylglycerol)IBA
04/2017
1Interleukin-6 (Interleukin 6)IBA
01/2017
1Glucose (Dextrose)FDA LinkGeneric
01/2017
1DNA (Deoxyribonucleic Acid)IBA
11/2015
1CP 31398IBA
03/2014
1Adenosine Triphosphatases (ATPase)IBA
03/2014
1ZyflamendIBA
09/2013
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
04/2013
1Sarcosine (Methylglycine)IBA
12/2012
1alpha-hydroxyglutarateIBA
12/2012
1Biological ProductsIBA
04/2012
1Cyclic AMP (AMP, Cyclic)IBA
04/2012
1Immunoglobulin G (IgG)IBA
05/2011
1Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
05/2011
1Aromatase InhibitorsIBA
03/2011
1Indicators and Reagents (Reagents)IBA
05/2010
1Contrast MediaIBA
05/2010
1CreatinineIBA
11/2009
16-formylindolo(3,2-b)carbazoleIBA
10/2009
1Bile Acids and Salts (Bile Acids)IBA
09/2009
1Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
04/2009

Therapy/Procedure

4Chemoprevention
03/2010 - 01/2005
3Therapeutics
04/2015 - 06/2005
2Caloric Restriction
01/2022 - 04/2013
2Mastectomy (Mammectomy)
04/2017 - 01/2017
2Aftercare (After-Treatment)
10/2007 - 01/2005
2Drug Therapy (Chemotherapy)
06/2005 - 08/2002
1Analgesia
10/2013